Police were called to Highway 410 near Sandalwood Parkway at about 2:30 a.m. for a person who was shot.
When officers arrived, they located two people and a vehicle on the northbound lanes of Highway 410, said Const. Heather Cannon.
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She said one person with gunshot wounds was transported to a trauma centre with serious injuries, while a second person, who was also shot, was pronounced dead.
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While on scene, officers had an "interaction" with a separate vehicle, and due to that interaction the SIU was notified, Cannon said.
SIU spokesperson Monica Hudon said when officers arrived at the scene, the driver of an Audi SUV attempted to drive off and police tried to block it from moving forward.
"When they did so, the Audi reversed and at that time one officer discharged his firearm multiple times at the Audi," Hudon said.
"The SIU has three investigators and three forensic investigators assigned to this case," Hudon said.
The people in the Audi have not yet been found, and Hudon said investigators do not know if anyone in the vehicle was hurt.
Police closed down Highway 410 in both directions in the area for the investigation but all lanes have since been reopened.
“Somebody may or may not have been injured and so we need to be called in so that we can start fresh right at the beginning to see if this is something we need to continue to investigate,” Hudon said.
The SIU is arms-length agency investigates reports involving police where there has been death, serious injury or allegations of sexual assault.
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One person is dead and another person is in critical condition after an apparent shooting involving moving vehicles on Highway 410 in Brampton.
The shooting took place in the northbound lanes of the highway between Bovaird Drive and Sandalwood Parkway at around 2:30 a.m.
Police arriving on scene located the two shooting victims in a vehicle stopped on the highway and then attempted to box in an Audi that was observed on scene and deemed to be suspicious.
The Special Investigation Unit says that vehicle then reversed, prompting a Peel Regional Police officer to fire multiple shots at it in an unsuccessful attempt at halting its progress.
The vehicle was later found abandoned and riddled with bullet holes on Checkerberry Crescent, which is just east of Highway 410.
The SIU is looking into the circumstances surrounding the police interaction with the Audi while Peel Regional Police are leading the investigation into the initial shooting.
The SIU is mandated to investigate any interaction where there has been serious injury or death. We dont know what happened in this particular case yet as we havent located the occupants of the vehicle but police have an obligation to notify us whenever there is an incident that could possibly fall under the SIUs mandate, spokesperson Monica Hudon said at the scene on Monday afternoon. An officer discharged his firearm, a vehicle was struck and somebody may or may not have been injured so we need to be called in so that we can start fresh right at the beginning and we will see whether this is something that we will continue to investigate.
Hudon said that investigators will be examining the suspect vehicle as part of their investigation and are also looking to speak with anyone who witnessed the events that transpired on Highway 410.
All I know right now is that multiple shots were fired at the vehicle, she said. Whether you witnessed what happened on the highway between police and the vehicle or what happened leading up to when the vehicle was abandoned we would like to hear from you.
Police have said that the two victims in the initial shooting, believed to be men in their 20s, were both found in a vehicle that was stopped just south of Sandalwood Parkway.
Const. Heather Cannon told reporters earlier on Monday that police are dealing with multiple crime scenes, though she refused to comment on how many.
She also refused to comment on whether a reported carjacking involving a black Honda Pilot being operated as an Uber in the area where the suspect vehicle was located could be related to the police investigation.
She said that right now investigators with the SIU are working alongside forensics investigators, who are searching for evidence on Highway 410.
At this particular point homicide is canvassing the area. Anyone that has any dash cam video or anything that can assist the investigation we are looking for, she said.
Highway 410 was closed in both directions between Bovaird Drive and Mayfield Road for most of the day, but reopened around 8:30 p.m.
A Peel Regional Police cruiser is shown at the scene of a deadly shooting investigation on Highway 410 in Brampton on Monday afternoon. (Steve Ryan)